Contribution of different brain pathologies to the neuroimaging and
neuropsychological profile of in pre-symptomatic individuals developing 
   Lead Investigator:    Frederic St-Onge
   Institution      :    Douglas Mental Health University Institute
   E-Mail           :    frederic.st-onge@mail.mcgill.ca
   Proposal ID      :    1375



   Proposal Description:
   Overall: Understand the contribution of different brain pathologies observed at death on the clinical and biomarker profiles of Alzheimer's disease phenotype, from normal cognition to dementia.                                                Aim 1. Associate neuropathological patterns to specific clinical progression profile in participants developing MCI or dementia before death                   Aim 2. Associate neuropathological patterns to neuroimaging (MRI and PET) biomarkers in participants developing MCI or dementia before death